GDNF Family Receptor alpha Antibody Blocking Peptide(bs-0201P)-500ug

GDNF Family Receptor alpha Ant

ibody Blocking Peptide(bs-0201P)-500ug
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  • bs-0201P
  • 2025年10月16日
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      500ug

    产品编号bs-0201P
    英文名称GDNF Family Receptor alpha Antibody Blocking Peptide
    中文名称GDNF家族受体α-1封闭多肽
    英文别名GDNF Receptor alpha 1; GFRa-1; GFR alpha; GDNFR alpha; TmR1; GFR alpha-1; RETL1; RET ligand 1; TGF-beta related neurotrophic factor receptor-1; AU042498; DKFZp313E1012; DKFZp686J0156; FLJ10561; FLJ31546; GDNFR; Gdnfr alpha; GFR-ALPHA-1; GFRA1; GRFA1; LOC143381; MGC23045; Ret; RET1L; RETL1; TRNR1; GFRA1_HUMAN; GDNF family receptor alpha-1; GDNF receptor alpha-1; GDNFR-alpha-1; TGF-beta-related neurotrophic factor receptor 1.
    性状Lyophilized
    纯化方法HPLC
    研究领域

    Neuroscience > Neurology process > Growth and Development > Neurotrophins

    亚基2 molecules of GDNFR-alpha are thought to form a complex with the disulfide-linked GDNF dimer and with 2 molecules of RET.
    亚细胞定位Cell membrane; Lipid-anchor, GPI-anchor.
    相似性Belongs to the GDNFR family.
    功能Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    背景资料Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq]

     

     

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