STAT6 Antibody Blocking Peptide(bs-1143P)-500ug

STAT6 Antibody Blocking Peptid

e(bs-1143P)-500ug
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  • ¥880
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  • bs-1143P
  • 2025年10月16日
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      500ug

    产品编号bs-1143P
    英文名称STAT6 Antibody Blocking Peptide
    中文名称信号转导和转录激活因子6封闭多肽
    英文别名signal transducers and activators of transduction 6; D12S1644; IL 4 STAT; IL4 STAT; Interleukin 4 Induced; Interleukin 4 Induced Transcription Factor IL4 STAT; Signal Transducer And Activator Of Transcription 6 Interleukin 4 Induced; Signal Transducer And Activator Of Transcription 6 Nirs Variant 1; STAT 6; STAT interleukin4 induced; STAT6B; STAT6C; Transcription factor IL 4 STAT.
    性状Lyophilized
    纯化方法HPLC
    研究领域

    Cancer > Signal transduction > Nuclear signaling > STAT family

    Epigenetics and Nuclear Signaling > Nuclear Signaling Pathways > STATs

    Epigenetics and Nuclear Signaling > Transcription > Transcription Factors

    Kits/ Lysates/ Other > Kits > ELISA Kits > In Cell ELISA Kits > Phosphoprotein ICE kits

    Signal Transduction > Signaling Pathway > Nuclear Signaling > STATs

    亚基Forms a homodimer or a heterodimer with a related family member (By similarity). Interacts with NCOA1 via its C-terminal LXXLL motif.
    亚细胞定位Cytoplasm. Nucleus. Note=Translocated into the nucleus in response to phosphorylation.
    翻译后修饰Tyrosine phosphorylated following stimulation by IL-4 and IL-3.
    相似性Belongs to the transcription factor STAT family.
    Contains 1 SH2 domain.
    功能Carries out a dual function: signal transduction and activation of transcription. Involved in interleukin-4 signalling.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    背景资料The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X (L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Also known as: signal transducers and activators of transduction 6; D12S1644; IL 4 STAT; IL4 STAT; Interleukin 4 Induced; Interleukin 4 Induced Transcription Factor IL4 STAT; Signal Transducer And Activator Of Transcription 6 Interleukin 4 Induced; Signal Transducer And Activator Of Transcription 6 Nirs Variant 1; STAT 6; STAT interleukin4 induced; STAT6B; STAT6C; Transcription factor IL 4 STAT.

     

     

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