- ￥880
- Bioss
- bs-12333P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-12333P |
| 英文名称 | ERMAP Antibody Blocking Peptide |
| 中文名称 | 红细胞膜相关蛋白ERMAP封闭多肽 |
| 英文别名 | ERMAP; ERMAP_HUMAN; Erythroblast membrane associated protein; Erythroid membrane associated protein; Erythroid membrane-associated protein; hERMAP; MGC118810; MGC118811; MGC118812; MGC118813; PRO2801; Radin blood group (Rd); Radin blood group antigen; RD; SC; Scianna blood group (Sc); Scianna blood group antigen. |
| 纯化方法 | HPLC |
| 亚细胞定位 | Cell membrane. Cytoplasm. |
| 组织特异性 | Expressed in erythroid-enriched bone marrow (at protein level). Highly expressed in bone marrow and to a lower extent in leukocytes, thymus, lymph node and spleen. |
| 翻译后修饰 | Glycosylated. |
| 相似性 | Belongs to the immunoglobulin superfamily. BTN/MOG family. Contains 1 B30.2/SPRY domain. Contains 1 Ig-like V-type (immunoglobulin-like) domain. |
| 功能 | Possible role as a cell-adhesion or receptor molecule of erythroid cells. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | ERMAP is a single-pass type one membrane protein that belongs to the immunoglobulin superfamily. Expressed in cord blood, fetal liver and adult bone marrow, ERMAP is thought to function as a cell adhesion molecule in erythroid cells and is responsible for expression of the Scianna/Radin (Sc/Rd) blood group antigen system. The Sc/Rd system is comprised of seven antigens that are present on the surface of red blood cells and have a variety of functions ranging from protein transport to cell adhesion. These seven blood antigens can differ in their expression within a population and may sometimes differ between mother and child. A fetus expressing different blood antigens than its mother may cause the mother to produce antibodies against the fetal blood. This condition is known as hemolytic disease of the newborn (HDN) and is characterized by jaundice, anemia and in some cases, infant death. |
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ERMAP Antibody Blocking Peptide(bs-12333P)-500ug
￥880
