DISP3 Antibody Blocking Peptid

e(bs-12324P)-500ug

价格￥880

品牌Bioss
货号bs-12324P
更新日期2025年10月16日

北京博奥森生物技术有限公司

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规格：
500ug

产品编号	bs-12324P
英文名称	DISP3 Antibody Blocking Peptide
中文名称	多通道膜蛋白PTCHD2封闭多肽
英文别名	DISP3; Dispatched, drosophila, homolog of, 3; G630052C06Rik; hCG_24779; KIAA1337; Patched domain-containing protein 2; Protein dispatched homolog 3; Ptchd2; PTHD2_HUMAN; RGD1305820; RND-type protein RNDEu-2; RNDEu-2; patched domain containing 2; RP23-157B15.1; PTCHD2.
纯化方法	HPLC
亚细胞定位	Membrane; Multi-pass membrane protein (Potential).
组织特异性	Expressed in brain and testis.
相似性	Belongs to the patched family. Contains 1 SSD (sterol-sensing) domain.
保存条件	Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料	PTCHD2 is a 1,392 amino acid multi-pass membrane protein that contains one SSD (sterol-sensing) domain and belongs to the patched family. Expressed in retina, brain and testis, PTCHD2 localizes to endoplasmic reticulum and colocalizes with cholesterol. PTCHD2 overexpression leads to increased cholesterol levels, suggesting that PTCHD2 may play a role in cholesterol homeostasis. PTCHD2 is further hypothesized to act as a link between thyroid hormone and cholesterol metabolism. Existing as two alternatively spliced isoforms, PTCHD2 is thought to assist in the release of lipid-anchored secreted proteins and is encoded by a gene that maps to human chromosome 1p36.22.

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文献和实验

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