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- Bioss
- bs-12318P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-12318P |
| 英文名称 | SCUBE2 Antibody Blocking Peptide |
| 中文名称 | 内皮分泌蛋白SCUBE2封闭多肽 |
| 英文别名 | 4932442O19Rik; Cegb1; Cegf1; CEGP1; Cegp1 protein; CUB domain and EGF-like repeat containing 1; FLJ16792; FLJ35234; ICRFP703B1614Q5.1; MGC133057; Protein CEGP1; RGD1563998; SCUB2_HUMAN; Scube2; Signal peptide, CUB and EGF-like domain-containing protein 2; Signal peptide, CUB domain, EGF-like 2. |
| 纯化方法 | HPLC |
| 研究领域 | Stem Cells > Signaling Pathways > Hedgehog > Secreted |
| 亚基 | Forms homooligomers and heterooligomers with SCUBE1 and SCUBE3 (By similarity). |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Expressed in a broad spectrum of adult tissues. |
| 相似性 | Contains 1 CUB domain. Contains 9 EGF-like domains. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | SCUBE2 is a 999 amino acid protein that is ubiquitously expressed in adult tissues and belongs to the evolutionarily conserved SCUBE protein family. Containing a CUB domain and nine EGF-like domains, SCUBE2 manifests as a secreted surface-anchored glycoprotein when overexpressed and is considered a novel component of the HH (Hedgehog) signal. The HH signal plays a pivotal role in induction of ventral neuronal and muscle cell types around the midline during vertebrate development. It is suggested that SCUBE2 expression is important in breast cancer progression and may serve as a useful prognostic marker. SCUBE2 forms homo-oligomers and hetero-oligomers with SCUBE1 and SCUBE3. Expressed as three isoforms produced by alternative splicing events, SCUBE2 is encoded by a gene located on human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. |
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SCUBE2 Antibody Blocking Peptide(bs-12318P)-500ug
￥880
