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500ug
| 产品编号 | bs-13579P |
| 英文名称 | ZBTB46/ZNF340/BTBD4 Antibody Blocking Peptide |
| 中文名称 | 锌指蛋白340封闭多肽 |
| 英文别名 | BTB/POZ domain containing protein 4; BTBD4; RINZF; Zinc finger and BTB domain containing 46; Zinc finger and BTB domain containing protein 46; Zinc finger protein 340; ZNF340; ZBT46_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > Transcription > Domain Families > Zinc Finger |
| 组织特异性 | Nucleus (Potential). |
| 翻译后修饰 | Sumoylated. Desumoylation by PPPDE2 reverses transcriptional repression activity (By similarity). |
| 相似性 | Contains 1 BTB (POZ) domain. Contains 2 C2H2-type zinc fingers. |
| 功能 | ZBTB46 may be involved in transcriptional regulation. It contains one BTB (POZ) domain and two C2H2 type zinc fingers. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | BTBD4 is a 589 amino acid protein that contains one BTB/POZ domain. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD4 may play a role in transcription regulation. |
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ZBTB46/ZNF340/BTBD4 Antibody Blocking Peptide(bs-13579P)-500ug
¥880







