ZBTB46/ZNF340/BTBD4 Antibody Blocking Peptide(bs-13579P)-500ug

ZBTB46/ZNF340/BTBD4 Antibody B

locking Peptide(bs-13579P)-500ug
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  • ¥880
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  • bs-13579P
  • 2025年10月16日
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      500ug

    产品编号bs-13579P
    英文名称ZBTB46/ZNF340/BTBD4 Antibody Blocking Peptide
    中文名称锌指蛋白340封闭多肽
    英文别名BTB/POZ domain containing protein 4; BTBD4; RINZF; Zinc finger and BTB domain containing 46; Zinc finger and BTB domain containing protein 46; Zinc finger protein 340; ZNF340; ZBT46_HUMAN.
    纯化方法HPLC
    研究领域

    Epigenetics and Nuclear Signaling > Transcription > Domain Families > Zinc Finger

    组织特异性Nucleus (Potential).
    翻译后修饰Sumoylated. Desumoylation by PPPDE2 reverses transcriptional repression activity (By similarity).
    相似性Contains 1 BTB (POZ) domain.
    Contains 2 C2H2-type zinc fingers.
    功能ZBTB46 may be involved in transcriptional regulation. It contains one BTB (POZ) domain and two C2H2 type zinc fingers.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料BTBD4 is a 589 amino acid protein that contains one BTB/POZ domain. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD4 may play a role in transcription regulation.

     

     

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