USE1 Antibody Blocking Peptide(bs-12305P)-500ug

USE1 Antibody Blocking Peptide

(bs-12305P)-500ug
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  • bs-12305P
  • 2025年10月16日
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      500ug

    产品编号bs-12305P
    英文名称USE1 Antibody Blocking Peptide
    中文名称囊泡转运蛋白Use1封闭多肽
    英文别名2010315L10Rik; 5730403H22Rik; AV002165; D12; Ed2; Embryonic development factor 2; MDS032; P31; Protein D12; Protein p31; putative MAPK activating protein PM26; Putative MAPK-activating protein PM26; Q-snare; RGD1306660; SLT1; SNARE-like tail-anchored protein 1 homolog; Unconventional SNARE in the ER 1 homolog (S. cerevisiae); Unconventional SNARE in the ER 1 homolog; Use1; USE1 like protein; Use1 unconventional SNARE in the ER 1 homolog (S. cerevisiae); USE1-like protein; USE1_HUMAN; USE1L; Vesicle transport protein USE1.
    纯化方法HPLC
    研究领域

    Signal Transduction > Protein Trafficking > Vesicle Transport > SNAPs & SNAREs

    亚基Component of a SNARE complex consisting of STX18, USE1L, BNIP1/SEC20L and SEC22B. Interacts directly with STX18.
    亚细胞定位Endoplasmic reticulum membrane.
    相似性Belongs to the USE1 family.
    功能SNARE that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料In eukaryotic cells, the Golgi apparatus receives newly synthesized proteins from the endoplasmic reticulum (ER) and, after covalent modification, delivers them to their destination in the cell. For membrane-directed proteins this process is believed to be carried out via vesicular transport. Correct vesicular transport is determined by specific pairing of vesicle-associated SNAREs (v-SNAREs) with those on the target membrane (t-SNAREs). Unconventional SNARE in the ER 1, also known as USE1 or protein p31, is a 259 amino acid t-SNARE that forms a larger complex with ZW10, RINT-1 and Syntaxin 18. Upon Mg2+-AP treatment in the presence of NSF and ?SNAP, ZW10, RINT-1 and USE1 dissociate from Syntaxin 18. USE1 is a single-pass type IV membrane protein that is localized to the endoplasmic reticulum membrane. Three named isoforms exist for USE1 as a result of alternative splicing events.

     

     

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