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500ug
| 产品编号 | bs-12305P |
| 英文名称 | USE1 Antibody Blocking Peptide |
| 中文名称 | 囊泡转运蛋白Use1封闭多肽 |
| 英文别名 | 2010315L10Rik; 5730403H22Rik; AV002165; D12; Ed2; Embryonic development factor 2; MDS032; P31; Protein D12; Protein p31; putative MAPK activating protein PM26; Putative MAPK-activating protein PM26; Q-snare; RGD1306660; SLT1; SNARE-like tail-anchored protein 1 homolog; Unconventional SNARE in the ER 1 homolog (S. cerevisiae); Unconventional SNARE in the ER 1 homolog; Use1; USE1 like protein; Use1 unconventional SNARE in the ER 1 homolog (S. cerevisiae); USE1-like protein; USE1_HUMAN; USE1L; Vesicle transport protein USE1. |
| 纯化方法 | HPLC |
| 研究领域 | Signal Transduction > Protein Trafficking > Vesicle Transport > SNAPs & SNAREs |
| 亚基 | Component of a SNARE complex consisting of STX18, USE1L, BNIP1/SEC20L and SEC22B. Interacts directly with STX18. |
| 亚细胞定位 | Endoplasmic reticulum membrane. |
| 相似性 | Belongs to the USE1 family. |
| 功能 | SNARE that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | In eukaryotic cells, the Golgi apparatus receives newly synthesized proteins from the endoplasmic reticulum (ER) and, after covalent modification, delivers them to their destination in the cell. For membrane-directed proteins this process is believed to be carried out via vesicular transport. Correct vesicular transport is determined by specific pairing of vesicle-associated SNAREs (v-SNAREs) with those on the target membrane (t-SNAREs). Unconventional SNARE in the ER 1, also known as USE1 or protein p31, is a 259 amino acid t-SNARE that forms a larger complex with ZW10, RINT-1 and Syntaxin 18. Upon Mg2+-AP treatment in the presence of NSF and ?SNAP, ZW10, RINT-1 and USE1 dissociate from Syntaxin 18. USE1 is a single-pass type IV membrane protein that is localized to the endoplasmic reticulum membrane. Three named isoforms exist for USE1 as a result of alternative splicing events. |
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USE1 Antibody Blocking Peptide(bs-12305P)-500ug
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