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- Bioss
- bs-12290P
- 2025年10月16日
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500ug
| 产品编号 | bs-12290P |
| 英文名称 | RBMY1F Antibody Blocking Peptide |
| 中文名称 | RNA结合蛋白片段Y染色体家族蛋白2封闭多肽 |
| 英文别名 | YRRM2; RNA binding motif protein, Y chromosome, family 1 member F/J; RNA binding motif protein, Y linked, family 1, member F; Y chromosome RNA recognition motif 2; YRRM2; RBY1F_HUMAN. |
| 纯化方法 | HPLC |
| 亚基 | Interacts with splicing factor proteins SFRS3/SRP20, TRA2B/SFRS10, KHDRBS1/SAM68 and KHDRBS3. |
| 亚细胞定位 | Nuclear |
| 组织特异性 | Testis-specific. |
| 相似性 | Contains 1 RRM (RNA recognition motif) domain. |
| 功能 | RBMY1F is an RNA binding protein which may be involved in spermatogenesis. It is required for sperm development, possibly by participating in pre mRNA splicing in the testis. The RBMY1 proteins are encoded by strongly repeated regions of the Y chromosome, mostly within the AZFb region. The exact number of functional copies is unclear and may vary between individuals, and some of them may represent pseudogenes. The proteins are very similar, and most experimental data does not discriminate between the different members. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The RBM (RNA-binding motif) gene family encodes proteins with an RNA binding motif. RBMY (RBM, Y chromosome) encodes a germ-cell specific nuclear protein involved in spermatogenesis. The RBM gene family, including RBMY1A, RBMY1B, RBMY1D, RBMY1E, RBMY1F, RBMY1H and RBMY1J, is comprised of at least 30 genes and pseudogenes, found on both arms of the Y chromosome. RBM X, an ancestral X chromosome homolog of the RBMY gene, encodes hnRNP G, which is widely expressed, whereas the RBMY gene evolved a male-specific function in spermatogenesis. Micro-deletions of the AZFb region of the Y chromosome, which contains a number of RBMY genes, usually result in severe consequences for spermatogenesis. RBM expression is localized to the nuclei of germ cells and RBM interacts with Tra2beta. Tra2beta is a ubiquitous activator of pre-mRNA splicing, but is most highly expressed in testis, suggesting a role for RBM in Tra2beta-dependent splicing in spermatocytes. The human RBMX gene maps to chromosome Xq26 and the RBMY gene family is found on all mammalian Y chomosomes. |
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RBMY1F Antibody Blocking Peptide(bs-12290P)-500ug
￥880
