- ￥880
- Bioss
- bs-12286P
- 2025年10月16日
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-12286P |
| 英文名称 | DDX3Y Antibody Blocking Peptide |
| 中文名称 | 精子发育相关蛋白DDX3Y封闭多肽 |
| 英文别名 | DBY; DEAD (Asp-Glu-Ala-Asp) box polypeptide 3 Y linked; DEAD box protein 3 Y chromosomal; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide Y chromosome; DDX3Y_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Developmental Biology > Reproduction > Germ cell markers Stem Cells > Germline Stem Cells > Spermatogonial Stem Cells |
| 亚基 | May interact with TDRD3. |
| 亚细胞定位 | Cytoplasm. Nucleus. |
| 组织特异性 | Testis-specific. Expressed predominantly in spermatogonia. |
| 相似性 | Belongs to the DEAD box helicase family. DDX3/DED1 subfamily. Contains 1 helicase ATP-binding domain. Contains 1 helicase C-terminal domain. |
| 功能 | DEAD box proteins are putative RNA helicases, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD). They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as ribosome and spliceosome assembly, translation initiation and nuclear and mitochondrial splicing. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, and it has a homolog on the X chromosome. Mutations in DDX3Y cause male infertility, Sertoli cell-only syndrome or severe hypospermatogenesis, suggesting that it plays a key role in the spermatogenic process. Alternatively spliced variants, encoding the same protein, have been identified. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | DDX3X is encoded by a gene found on the X chromosome while DDX3Y is encoded by a gene on the Y chromosome. DDX3Y is exclusively expressed in testis and is required for normal spermatogenesis. DDX3X is ubiquitously expressed and predominantly localizes to the nuclear speckles, participating in RNA splicing, transcription, translation initiation, mRNA transport and cell cycle regulation. DDX3X also partakes in HIV-1 replication and hepatitis C viral infections. |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
DDX3Y Antibody Blocking Peptide(bs-12286P)-500ug
￥880
