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- Bioss
- bs-13574P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-13574P |
| 英文名称 | ZBTB4/ZNF903 Antibody Blocking Peptide |
| 中文名称 | 锌指蛋白903封闭多肽 |
| 英文别名 | KAISO-L1; KAISO-like zinc finger protein 1; KIAA1538; ZBTB4; ZBTB4_HUMAN; Zinc finger and BTB domain containing 4; Zinc finger and BTB domain-containing protein 4; ZNF903. |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > DNA methylation > Methylated DNA Binding Epigenetics and Nuclear Signaling > Transcription > Domain Families > Zinc Finger |
| 亚基 | Interacts with HIPK2. |
| 亚细胞定位 | Nucleus. |
| 翻译后修饰 | Phosphorylated by HIPK2. This phosphorylation reduces stability and triggers ZBTB4 protein degradation in response to DNA damage. |
| 相似性 | Contains 1 BTB (POZ) domain. Contains 6 C2H2-type zinc fingers. |
| 功能 | May be involved in transcriptional regulation. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZBTB4 (zinc finger and BTB domain containing 4), also known as KAISO-L1 (KAISO-like zinc finger protein 1), is a 1,013 amino acid nuclear protein that is involved in transcriptional regulation. ZBTB4 contains one BTB (POZ) domain, six C2H2-type zinc fingers and is phosphorylated and downregulated by HIPK2. The gene encoding ZBTB4 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. |
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ZBTB4/ZNF903 Antibody Blocking Peptide(bs-13574P)-500ug
￥880
