BEST3 Antibody Blocking Peptide(bs-11042P)-500ug

BEST3 Antibody Blocking Peptid

e(bs-11042P)-500ug
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  • ¥880
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  • bs-11042P
  • 2025年10月16日
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    • 规格

      500ug

    产品编号bs-11042P
    英文名称BEST3 Antibody Blocking Peptide
    中文名称卵黄状黄斑病蛋白3封闭多肽
    英文别名Vitelliform macular dystrophy 2 like protein 3; BEST 3; BEST3; BEST3_HUMAN; Bestrophin-3; Bestrophin3; Vitelliform macular dystrophy 2 like 3; Vitelliform macular dystrophy 2-like protein 3; VMD2L3.
    纯化方法HPLC
    亚细胞定位Cell membrane.
    组织特异性Present in skeletal muscle and weakly in brain, spinal cord, bone marrow and retina.
    相似性Belongs to the bestrophin family.
    功能Forms calcium-sensitive chloride channels. Permeable to bicarbonate.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Bestrophin-3 is a 668 amino acid member of the Bestrophin family of proteins. Members of the Bestrophin family are transmembrane proteins that contain a high percentage of aromatic residues, a conserved RFP (arg-phe-pro) motif and they function as anion channels. Expressed predominantly in skeletal muscle but also found in spinal cord, brain, testis, thymus, retina and bone marrow, Bestrophin-3 forms calcium-sensitive chloride channels. In addition, Bestrophin-3 contains an AI (auto-inhibitory) domain that is capable of regulating the anion channel activity. Due to alternative splicing events, three isoforms exist for Bestrophin-3.

     

     

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