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- bs-11037P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-11037P |
| 英文名称 | TANC1 Antibody Blocking Peptide |
| 中文名称 | TANC1蛋白封闭多肽 |
| 英文别名 | ROLSB; Protein TANC1; Rolling pebbles homolog B; TANC; Tanc1; TANC1_HUMAN; Tetratricopeptide repeat ankyrin repeat and coiled coil containing 1; Tetratricopeptide repeat ankyrin repeat and coiled coil domain containing protein 1; TPR domain ankyrin repeat and coiled coil containing. |
| 纯化方法 | HPLC |
| 亚基 | Interacts probably directly with DLG1, DLG4, HOMER1. Interacts with DLGAP1, INA, CAMK2A, GRIN2B and GRIA1. Interacts with TNIK. Interacts with MINK1. |
| 亚细胞定位 | Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. |
| 翻译后修饰 | Phosphorylated; by MINK1 and TNIK upon stimulation by RAP2A. |
| 相似性 | Belongs to the TANC family.
Contains 11 ANK repeats. Contains 3 TPR repeats. |
| 功能 | May be a scaffold component in the postsynaptic density. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | TANC (tetratricopeptide repeat, ankyrin repeat and coiled-coil domain-containing protein), also known as TANC1, is a 1,861 amino acid postsynaptic cell membrane protein that contains eleven ANK repeats, three TPR repeats and belongs to the TANC family. Considered a scaffolding component in the postsynaptic density, TANC interacts with TNIK, SAPAP1, Alpha-internexin, CaMKII, NMDA 2 and GluR-1. It is also thought that TANC interacts directly with SAP 97, PSD-95 and Homer. Upon stimulation by Rap 2, MINK1 and TNIK may phosphorylate TANC. The TANC gene encodes two alternatively spliced isoforms, contains approximately 264,025 bases and maps to human chromosome 2q24.2. Making up approximately 8% of the human genome, chromosome 2 consists of 237 million bases and encodes over 1,400 genes. A number of genetic diseases are linked to genes on chromosome 2 including Harlequin icthyosis, sitosterolemia and Alstr鰉 syndrome. |
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TANC1 Antibody Blocking Peptide(bs-11037P)-500ug
￥880
