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500ug
| 产品编号 | bs-14713P |
| 英文名称 | FAM125A Antibody Blocking Peptide |
| 中文名称 | FAM125A蛋白封闭多肽 |
| 英文别名 | CFBP; CIN85/CD2AP family-binding protein; ESCRT-I complex subunit MVB12A; F125A_HUMAN; FAM125A; Family with sequence similarity 125, member A; Multivesicular body subunit 12A; Protein FAM125A. |
| 纯化方法 | HPLC |
| 亚细胞定位 | Cytoplasm. Nucleus. Endosome. Cytoplasm > cytoskeleton > centrosome. Late endosome membrane. Colocalizes with F-actin. Some fraction may be nuclear. |
| 组织特异性 | Ubiquitously expressed except in skeletal muscle. |
| 翻译后修饰 | Phosphorylated on Tyr-204 upon EGF stimulation. Phosphorylation is required for interaction with CD2AP and CIN85/SH3KBP1. |
| 相似性 | Belongs to the FAM125 family. Contains 1 MABP domain. Contains 1 UMA domain. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down-regulation of EGF receptor. |
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FAM125A Antibody Blocking Peptide(bs-14713P)-500ug
¥880







