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- Bioss
- bs-14705P
- 2025年10月16日
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- 规格：
500ug
| 产品编号 | bs-14705P |
| 英文名称 | FAM120A Antibody Blocking Peptide |
| 中文名称 | FAM120A蛋白封闭多肽 |
| 英文别名 | C9orf10; Chromosome 9 open reading frame 10; Constitutive coactivator of PPAR gamma like protein 1; Constitutive coactivator of PPAR-gamma-like protein 1; DNA polymerase transactivated protein 5; DNA polymerase transactivated protein 1; DNAPTP1; DNAPTP5; F120A_HUMAN; FAM120A; Family with sequence similarity 120A; Hypothetical protein LOC23196; KIAA0183; LOC23196; MGC111527; MGC133257; OSSA; Oxidative stress-associated Src activator; Protein FAM120A. |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Other Antibodies > Other Antibodies Signal Transduction > Signaling Pathway > Lipid Signaling |
| 亚细胞定位 | Cytoplasm. Cell membrane. Translocates to plasma membrane upon ultraviolet exposure. |
| 组织特异性 | Ubiquitously expressed. Highly expressed in scirrhous-type gastric cancer tissues compared with normal gastric mucosa (at protein level). |
| 翻译后修饰 | Arg-982 is dimethylated, probably to asymmetric dimethylarginine. Phosphorylated on tyrosine by src family kinases upon ultraviolet exposure. |
| 相似性 | Belongs to the constitutive coactivator of PPAR-gamma family. |
| 功能 | May participate in mRNA transport in the cytoplasm (By similarity). Critical component of the oxidative stress-induced survival signaling. Activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. Binds RNA and promotes the secretion of IGF-II. May play a pivotal role in the progression of scirrhous-type gastric cancer by supporting cancer cell survival in environments with various oxidative stresses. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Chromosome 9 consists of about 145 million bases and 4% of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias. The FAM120A gene product has been provisionally designated FAM120A pending further characterization. |
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FAM120A Antibody Blocking Peptide(bs-14705P)-500ug
￥880
