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- Bioss
- bs-12281P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-12281P |
| 英文名称 | TBX6 Antibody Blocking Peptide |
| 中文名称 | 转录因子TBX6封闭多肽 |
| 英文别名 | DFNB 67; DFNB67; T box 6; T box protein 6; T box transcription factor TBX 6; T box transcription factor TBX6; T-box protein 6; T-box transcription factor TBX6; Tbox 6; TBX 6; tbx6; TBX6_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Developmental Biology > Reproduction > Germ cell markers Epigenetics and Nuclear Signaling > Transcription > Domain Families > Developmental Families Stem Cells > Germline Stem Cells > Embryonic Germ Cells Stem Cells > Neural Stem Cells > Intracellular |
| 亚基 | Forms a dimeric complex with DNA (in vitro). |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Expressed in fetal tail bud, posterior spinal tissue, intervertebral disk and testis. Also expressed in adult testis, kidney, lung, muscle and thymus. |
| 相似性 | Contains 1 T-box DNA-binding domain. |
| 功能 | Probable transcriptional regulator involved in developmental processes. Could be required for specification of paraxial mesoderm structures during gastrulation. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Members of the T-box (Tbx) gene family share a conserved domain that codes for the T-box, a sequence involved in DNA-binding and protein dimerization. The Tbx gene family is largely conserved throughout metazoan evolution, and is implicated in a variety of developmental processes ranging from the formation of germ layers to the organizational patterning of the central nervous system. In the mouse, Tbx6 is involved in both the specification and patterning of the somites along the entire length of the embryo. Specifically, Tbx6 is expressed in the primitive streak, tail bud, and presomitic mesoderm and is essential for the specification of posterior paraxial mesoderm. In the absence of Tbx6, posterior somites are replaced by ectopic neural tubes. |
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TBX6 Antibody Blocking Peptide(bs-12281P)-500ug
￥880
