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- Bioss
- bs-10529P
- 2025年10月16日
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- 技术资料
- 规格：
500ug
| 产品编号 | bs-10529P |
| 英文名称 | AOC3 Antibody Blocking Peptide |
| 中文名称 | 血管粘附蛋白1封闭多肽 |
| 英文别名 | vascular adhesion protein 1; Amine oxidase, copper containing 3 (vascular adhesion protein 1); AOC3; Copper amine oxidase; HPAO; Membrane copper amine oxidase; Semicarbazide sensitive amine oxidase; SSAO; Vascular adhesion protein 1; VP97; AOC3_HUMAN; Membrane primary amine oxidase; Semicarbazide-sensitive amine oxidase; VAP-1. |
| 性状 | Lyophilized |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Neurology process > Neurodegenerative disease > Alzheimer's disease Signal Transduction > Cytoskeleton / ECM > Cell Adhesion > Cell Adhesion Molecules > Endothelial Signal Transduction > Cytoskeleton / ECM > Cell Adhesion > Cell Adhesion Molecules > Vascular |
| 亚细胞定位 | Cell adhesion protein that participates in lymphocyte recirculation by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells in an L-selectin-independent fashion. Has a monoamine oxidase activity. May play a role in adipogenesis. |
| 组织特异性 | Strongly expressed on the high endothelial venules of peripheral lymph nodes and on hepatic endothelia. Also highly expressed in appendix, lung and small intestine. Expressed also in adipose tissue, in bone marrow, colon, heart, kidney, ovary, pancreas, placenta, prostate, skeletal muscle, spleen and testis. |
| 翻译后修饰 | Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.
N- and O-glycosylated. |
| 相似性 | Belongs to the copper/topaquinone oxidase family. |
| 功能 | Cell adhesion protein that participates in lymphocyte recirculation by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells in an L-selectin-independent fashion. Has a monoamine oxidase activity. May play a role in adipogenesis. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a member of the semicarbazide-sensitive amine oxidase family. Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone cofactor. The encoded protein is localized to the cell surface, has adhesive properties as well as monoamine oxidase activity, and may be involved in leukocyte trafficking. Alterations in levels of the encoded protein may be associated with many diseases, including diabetes mellitus. A pseudogene of this gene has been described and is located approximately 9-kb downstream on the same chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013] |
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AOC3 Antibody Blocking Peptide(bs-10529P)-500ug
￥880
