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- Bioss
- bs-1715P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-1715P |
| 英文名称 | Cx26 Antibody Blocking Peptide |
| 中文名称 | 间隙连接蛋白26/GJB2封闭多肽 |
| 英文别名 | cx26; DFNA3; DFNB1; HID; KID; NSRD1; Connexin26; Connexin-26; GJB2; PPK; CXB2_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Sensory System > Auditory system Signal Transduction > Cytoskeleton / ECM > Cell Adhesion > Gap Junctions |
| 亚细胞定位 | Cell membrane. Cell junction, gap junction. |
| 组织特异性 | Expressed in the heart and fetal cochlea. |
| 翻译后修饰 | Belongs to the connexin family. Beta-type (group I) subfamily. |
| 相似性 | Belongs to the connexin family. Alpha-type (group II) subfamily. |
| 功能 | One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neiGHBoring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Gap junction channels consist of connexin protein subunits, which are encoded by a multigene family. GJBs (gap junction proteins or connexins) play crucial functional roles associated with these channels. Immunohistochemical staining of human cochlear cells demonstrated high levels of GJB2 expression. Mutations in GJB2 are associated with genetically derived hearing impairments, including autosomal recessive nonsyndromic deafness. |
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Cx26 Antibody Blocking Peptide(bs-1715P)-500ug
￥880
