Phospho-NCF4 (Thr154) Antibody Blocking Peptide(bs-3497P)-500ug

Phospho-NCF4 (Thr154) Antibody

Blocking Peptide(bs-3497P)-500ug
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  • bs-3497P
  • 2025年10月16日
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      500ug

    产品编号bs-3497P
    英文名称Phospho-NCF4 (Thr154) Antibody Blocking Peptide
    中文名称磷酸化嗜中性粒细胞胞浆因子4封闭多肽
    英文别名NCF4 (phospho T154); p- NCF4 (phospho T154); p40phox (Thr154); p-p40phox (Thr154); MGC3810; NCF 4; NCF; NCF-4; Ncf4; NCF4_HUMAN; Neutrophil cytosol factor 4; Neutrophil cytosolic factor 4; Neutrophil NADPH oxidase factor 4; p40-phox; p40phox; SH3 and PX domain-containing protein 4.
    纯化方法HPLC
    研究领域

    Cell Biology > Other Antibodies > Other Antibodies

    Cell Biology > Other Antibodies > Oxidative Stress

    Metabolism > Pathways and Processes > Mitochondrial Metabolism > Mitochondrial markers

    Metabolism > Pathways and Processes > Redox metabolism > Oxidative stress

    Metabolism > Types of disease > Cancer

    Signal Transduction > Metabolism > Mitochondrial

    亚基p40-PHOX associates primarily with p67-PHOX to form a complex with p47-PHOX.
    亚细胞定位Cytoplasm.
    组织特异性Expression is restricted to hematopoietic cells.
    相似性Contains 1 OPR domain.
    Contains 1 PX (phox homology) domain.
    Contains 1 SH3 domain.
    功能Component of the NADPH-oxidase, a multicomponent enzyme system responsible for the oxidative burst in which electrons are transported from NADPH to molecular oxygen, generating reactive oxidant intermediates. It may be important for the assembly and/or activation of the NADPH-oxidase complex.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料NCF4 is a cytosolic oxidase associated protein. It is a component of the nicotinamide adenine dinucleotide phosphate oxidase, which mediates down regulation of NADPH oxidase through interactions with its SH3 domain. NCF4 is associated with p67 phox but is absent in patients with chronic granulomatous disease who lack p67 phox.

     

     

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