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- Bioss
- bs-13197P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-13197P |
| 英文名称 | CEP20 Antibody Blocking Peptide |
| 中文名称 | 胚胎干细胞相关蛋白FOPNL封闭多肽 |
| 英文别名 | C16orf63; FGFR1OP N terminal like; FGFR1OP N-terminal-like protein; FOP-related protein of 20 kDa; Fopnl; FOPNL_HUMAN; FOR20; LisH domain containing protein C16orf63; LisH domain-containing protein FOPNL; PHSECRG2; Pluripotent embryonic stem cell related protein. |
| 纯化方法 | HPLC |
| 亚基 | Homooligomer; probably required for localization to centrosomes. |
| 亚细胞定位 | Cell projection; cilium. Cytoplasm; cytoskeleton; cilium basal body. Cytoplasm; cytoskeleton; centrosome. Cytoplasmic granule. Localizes to pericentriolar satellites, small (70-100 nm) cytoplasmic granules associated with the centrosome. |
| 组织特异性 | Widely expressed. Detected in brain, heart, kidney, liver, lung, skeletal muscle, placenta and intestine. |
| 相似性 | Belongs to the FGFR1OP family. Contains 1 LisH domain. |
| 功能 | Involved in the biogenesis of cilia. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | C16orf63, also known as FLJ31153 or DKFZp686N1651, is a 174 amino acid protein that contains one LisH domain. The gene that encodes C16orf63 maps to human chromosome 16. Chromosome 16 encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier. The C16orf63 gene product has been provisionally designated C16orf63 pending further characterization. |
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CEP20 Antibody Blocking Peptide(bs-13197P)-500ug
￥880
