NHLH1 Antibody Blocking Peptide(bs-11901P)-500ug

NHLH1 Antibody Blocking Peptid

e(bs-11901P)-500ug
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  • bs-11901P
  • 2025年10月16日
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      500ug

    产品编号bs-11901P
    英文名称NHLH1 Antibody Blocking Peptide
    中文名称环一螺旋蛋白1封闭多肽
    英文别名bHLHa35; Class A basic helix-loop-helix protein 35; Helix-loop-helix protein 1; HEN-1; HEN1; HEN1_HUMAN; Nescient helix loop helix 1; Nhlh1; NSCL; NSCL-1; NSCL1; OTTHUMP00000031860.
    纯化方法HPLC
    研究领域

    Epigenetics and Nuclear Signaling > Chromatin Binding Proteins > DNA / RNA binding

    Epigenetics and Nuclear Signaling > Transcription > Domain Families > HLH / Leucine Zipper > HLH

    Epigenetics and Nuclear Signaling > Transcription > Transcription Factors

    Metabolism > Pathways and Processes > Metabolic signaling pathways > Nucleotide metabolism

    Metabolism > Types of disease > Cancer

    Neuroscience > Neurology process > Metabolism

    Neuroscience > Neurology process > Neurogenesis

    亚基Efficient DNA binding requires dimerization with another bHLH protein.
    亚细胞定位Nucleus
    相似性Contains 1 bHLH (basic helix-loop-helix) domain.
    功能NHLH1 and NHLH2 are two basic domain helix-loop-helix (bHLH) proteins expressed predominantly in the developing nervous system and also in some cell lines derived from tumors with neural or neuroendocrine features such as neuroblastoma, PNET, and small cell lung cancer.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The helix-loop-helix (HLH) structures are known motifs commonly found in membrane-active and DNA-binding proteins. The helix-loop-helix proteins HEN1 and HEN2 are DNA-binding proteins that may be involved in cell-type determination in the early nervous system. Studies of expression in normal tissues have demonstrated expression of NHLH1/NSCL-1 and NHLH2/NSCL-2, the genes encoding HEN1 and HEN2, in the developing central and peripheral nervous system, specifically in developing neurons.

     

     

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