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- Bioss
- bs-11896P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-11896P |
| 英文名称 | NETO2 Antibody Blocking Peptide |
| 中文名称 | 脑特异性跨膜蛋白封闭多肽 |
| 英文别名 | Brain specific transmembrane protein; Brain specific transmembrane protein containing 2 CUB and 1 LDL receptor class A domains protein 2; Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2; BTCL2; FLJ10430; FLJ14724; FLJ90456; NEOT2; NETO 2; Neto2; NETO2_HUMAN; Neuropilin (NRP) and tolloid (TLL) like 2; Neuropilin and tolloid like protein 2; Neuropilin and tolloid-like protein 2. |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Neurology process > Neurogenesis |
| 亚基 | Interacts with GRIK2 and GRIK3, but neither with AMPA-nor with NMDA-sensitive glutamate receptors |
| 亚细胞定位 | Membrane. |
| 翻译后修饰 | N-glycosylated. |
| 相似性 | Contains 2 CUB domains. Contains 1 LDL-receptor class A domain. |
| 功能 | Accessory subunit of neuronal kainate-sensitive glutamate receptors, GRIK2 and GRIK3. Increases kainate-receptor channel activity, slowing the decay kinetics of the receptors, without affecting their expression at the cell surface, and increasing the open probability of the receptor channels. Modulates the agonist sensitivity of kainate receptors. Slows the decay of kainate receptor-mediated excitatory postsynaptic currents (EPSCs), thus directly influencing synaptic transmission. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a predicted transmembrane protein containing two extracellular CUB domains followed by a low-density lipoprotein class A (LDLa) domain. A similar gene in rats encodes a protein that modulates glutamate signaling in the brain by regulating kainate receptor function. Expression of this gene may be a biomarker for proliferating infantile hemangiomas. A pseudogene of this gene is located on the long arm of chromosome 8. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011] |
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NETO2 Antibody Blocking Peptide(bs-11896P)-500ug
￥880
