DNHD1 Antibody Blocking Peptide(bs-14398P)-500ug

DNHD1 Antibody Blocking Peptid

e(bs-14398P)-500ug
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  • bs-14398P
  • 2025年10月16日
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      500ug

    产品编号bs-14398P
    英文名称DNHD1 Antibody Blocking Peptide
    中文名称DNHD1蛋白封闭多肽
    英文别名C11orf47; CCDC35; coiled-coil domain containing 35; DHCD1; DNHD1; DNHD1 variant protein; DNHD1_HUMAN; DNHD1L; Dynein heavy chain domain 1-like protein; Dynein heavy chain domain-containing protein 1; FLJ32752; FLJ35709; FLJ46184; Protein CCDC35.
    纯化方法HPLC
    研究领域

    Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Motor Proteins > Dynein

    翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
    相似性Belongs to the dynein heavy chain family.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Dyneins are multisubunit, high molecular weight ATPases that interact with microtubules to generate force by converting the chemical energy of ATP into the mechanical energy of movement. Cytoplasmic or axonemal Dynein heavy, intermediate, light and light-intermediate chains are all components of minus end-directed motors; the complex transports cellular cargos towards the central region of the cell. Axonemal dynein motors contain one to three non-identical heavy chains and cause a sliding of microtubules in the axonemes of cilia and flagella in a mechanism necessary for cilia to beat and propel the cell. DNHD1 is a 4,753 amino acid member of the dynein heavy chain protein family. Phosphorylated upon DNA damage, DNHD1 contains 12 LRR (leucine-rich) repeats. The gene that encodes DNHD1 maps to human chromosome 11, which contains 135 million base pairs and 1,400 genes.

     

     

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