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- Bioss
- bs-14397P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-14397P |
| 英文名称 | DND1 Antibody Blocking Peptide |
| 中文名称 | DND1蛋白封闭多肽 |
| 英文别名 | Dead end homolog 1 (zebrafish); Dead end protein; Dead end protein homolog 1; dnd1; DND1_HUMAN; MGC34750; RBMS4; RNA binding motif single stranded interacting protein 4; RNA-binding motif; single-stranded-interacting protein 4; Ter. |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Oncoproteins/suppressors > Oncoproteins Developmental Biology > Reproduction > Germ cell markers Stem Cells > Germline Stem Cells > Embryonic Germ Cells |
| 亚细胞定位 | Nucleus. Cytoplasm. Perinuclear germ granules, also called germ plasm or chromatoid body. Colocalizes in perinuclear sites with APOBEC3. |
| 相似性 | Contains 2 RRM (RNA recognition motif) domains. |
| 功能 | RNA-binding factor that positively regulates gene expression by prohibiting miRNA-mediated gene suppression. Relieves miRNA repression in germline cells (By similarity). Prohibits the function of several miRNAs by blocking the accessibility of target mRNAs. Sequence-specific RNA-binding factor that binds specifically to U-rich regions (URRs) in the 3' untranslated region (3'-UTR) of several mRNAs. Does not bind to miRNAs. May play a role during primordial germ cell (PGC) survival (By similarity). However, does not seem to be essential for PGC migration. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a protein that binds to microRNA-targeting sequences of mRNAs, inhibiting microRNA-mediated repression. Reduced expression of this gene has been implicated in tongue squamous cell carcinoma. Two pseudogenes of this gene are located on the long arm of chromosome 17. [provided by RefSeq, Dec 2010] |
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DND1 Antibody Blocking Peptide(bs-14397P)-500ug
￥880
