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- Bioss
- bs-16093P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-16093P |
| 英文名称 | FKBP1B Antibody Blocking Peptide |
| 中文名称 | FKBP1B/FKBP9蛋白封闭多肽 |
| 英文别名 | 12.6 kDa FK506-binding protein; 12.6 kDa FKBP; Calstabin 2; FK506 binding protein 1 like; FK506 binding protein 12.6; FK506 binding protein 1B 12.6 kDa; FK506 binding protein 1B; FK506-binding protein 1B; FKB1B_HUMAN; FKBP 12.6; FKBP 1B; FKBP 1L; FKBP 9; FKBP-12.6; FKBP-1B; FKBP12.6; Fkbp1b; FKBP1L; FKBP9; h FKBP 12; h-FKBP-12; Immunophilin FKBP12.6; OTK 4; OTK4; Peptidyl prolyl cis trans isomerase 1B; Peptidyl prolyl cis trans isomerase; Peptidyl-prolyl cis-trans isomerase FKBP1B; PKBP 1L; PKBP1L; PPIase 1B; PPIase; PPIase FKBP1B; Rotamase 1B; Rotamase |
| 纯化方法 | HPLC |
| 亚细胞定位 | Cytoplasm. |
| 组织特异性 | Isoform 1 and isoform 2 are Ubiquitous with highest levels in brain and thymus. |
| 相似性 | Belongs to the FKBP-type PPIase family. FKBP1 subfamily. Contains 1 PPIase FKBP-type domain. |
| 功能 | Associates with the ryanodine receptor (RYR-2) in cardiac muscle sarcoplasmic reticulum and may play a unique physiological role in excitation-contraction coupling in cardiac muscle. There are four molecules of FKBP12.6 per heart muscle RYR. Has the potential to contribute to the immunosuppressive and toxic effects of FK506 and rapamycin. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. There are two alternatively spliced transcript variants of this gene encoding different isoforms. [provided by RefSeq, Jul 2008] |
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FKBP1B Antibody Blocking Peptide(bs-16093P)-500ug
￥880
