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- Bioss
- bs-17152P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-17152P |
| 英文名称 | TRIOBP Antibody Blocking Peptide |
| 中文名称 | TRIOBP蛋白封闭多肽 |
| 英文别名 | DFNB28; KIAA1662; Protein TARA; TARA; TARA_HUMAN; Tara like protein; TRIO and F actin binding protein; Trio and filamentous actin binding protein; Trio associated repeat on actin. |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Sensory System > Auditory system Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Microfilaments > Actin etc > Actin Binding Proteins |
| 亚基 | Binds to TRIO and F-actin. May also interact with myosin II. Interacts with HECTD3. |
| 亚细胞定位 | Nucleus. Cytoplasm; cytoskeleton. Note: Localized to F-actin in a periodic pattern. |
| 组织特异性 | Widely expressed. Highly expressed in heart and placenta. Isoform 3 is expressed in fetal brain, retina and cochlea but is not detectable in the other tissues. |
| 翻译后修饰 | Ubiquitinated by HECTD3, leading to its degradation by the proteasome. Isoform 1: Phosphorylation at Thr-457 by PLK1 ensures mitotic progression and is essential for accurate chromosome segregation. |
| 相似性 | Contains 1 PH domain. |
| 功能 | TRIOBP is a protein that interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. This trio binding protein also associates with F actin and stabilizes F actin structures. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a protein with an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. The protein interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. The protein also associates with F-actin and stabilizes F-actin structures. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness. Multiple alternatively spliced transcript variants that would encode different isoforms have been found for this gene, however some transcripts may be subject to nonsense-mediated decay (NMD). [provided by RefSeq, Nov 2008] |
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TRIOBP Antibody Blocking Peptide(bs-17152P)-500ug
￥880
