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500ug
| 产品编号 | bs-17146P |
| 英文名称 | TRMT6 Antibody Blocking Peptide |
| 中文名称 | TRMT6蛋白封闭多肽 |
| 英文别名 | KIAA1153; Adenine N; CGI 09; CGI09; GCD10; Gcd10p; KIAA1153; MGC5029; TRM6; TRM6_HUMAN; trmt6; tRNA (adenine-N(1)-)-methyltransferase non-catalytic subunit TRM6; tRNA methyltransferase 6; tRNA methyltransferase 6 homolog (S. cerevisiae); tRNA(m1A58)-methyltransferase subunit TRM6; tRNA(m1A58)MTase subunit TRM6. |
| 纯化方法 | HPLC |
| 亚基 | tRNA (adenine-N(1)-)-methyltransferase is a heterodimer of TRM6 and TRM61. |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Expressed in brain, liver, testis and ovary. |
| 翻译后修饰 | Phosphorylated upon DNA damage, probably by ATM or ATR. |
| 相似性 | Belongs to the TRM6/GCD10 family. |
| 功能 | Substrate-binding subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a member of the tRNA methyltransferase 6 protein family. A similar protein in yeast is part of a two component methyltransferase, which is involved in the posttranslational modification that produces the modified nucleoside 1-methyladenosine in tRNAs. Modified 1-methyladenosine influences initiator methionine stability and may be involved in the replication of Human immunodeficiency virus type 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] |
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TRMT6 Antibody Blocking Peptide(bs-17146P)-500ug
¥880







