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500ug
| 产品编号 | bs-3437P |
| 英文名称 | Phospho-TYK2 (Tyr1054/1055) Antibody Blocking Peptide |
| 中文名称 | 磷酸化非受体酪氨酸蛋白激酶2封闭多肽 |
| 英文别名 | TYK2 (phospho Y1054 + Y1055); TYK2(Phospho-Tyr1054/1055); Tyk2(phospho Y1054/1055); TYK2 (phospho Tyr1054/1055); p-TYK2 (Tyr1054/1055); JTK 1; JTK1; TYK 2; Non receptor tyrosine protein kinase 2; Non receptor tyrosine protein kinase TYK2; Protein Tyrosine Kinase 2; Tyrosine kinase 2; TYK2_HUMAN; Non-receptor tyrosine-protein kinase TYK2. |
| 纯化方法 | HPLC |
| 研究领域 | Microbiology > Organism > Virus > RNA Virus > ssRNA positive strand virus > SARS Coronavirus Signal Transduction > Protein Phosphorylation > Tyrosine Kinases |
| 亚基 | Interacts with JAKMIP1. |
| 组织特异性 | Observed in all cell lines analyzed. Expressed in a variety of lymphoid and non-lymphoid cell lines. |
| 相似性 | Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily. Contains 1 FERM domain. Contains 2 protein kinase domains. Contains 1 SH2 domain. |
| 功能 | Probably involved in intracellular signal transduction by being involved in the initiation of type I IFN signaling. Phosphorylates the interferon-alpha/beta receptor alpha chain. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq]. |
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Phospho-TYK2 (Tyr1054/1055) Antibody Blocking Peptide(bs-3437P)-500ug
¥1080







