Phospho-TYK2 (Tyr1054/1055) Antibody Blocking Peptide(bs-3437P)-500ug

Phospho-TYK2 (Tyr1054/1055) An

tibody Blocking Peptide(bs-3437P)-500ug
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  • bs-3437P
  • 2025年10月16日
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      500ug

    产品编号bs-3437P
    英文名称Phospho-TYK2 (Tyr1054/1055) Antibody Blocking Peptide
    中文名称磷酸化非受体酪氨酸蛋白激酶2封闭多肽
    英文别名TYK2 (phospho Y1054 + Y1055); TYK2(Phospho-Tyr1054/1055); Tyk2(phospho Y1054/1055); TYK2 (phospho Tyr1054/1055); p-TYK2 (Tyr1054/1055); JTK 1; JTK1; TYK 2; Non receptor tyrosine protein kinase 2; Non receptor tyrosine protein kinase TYK2; Protein Tyrosine Kinase 2; Tyrosine kinase 2; TYK2_HUMAN; Non-receptor tyrosine-protein kinase TYK2.
    纯化方法HPLC
    研究领域

    Microbiology > Organism > Virus > RNA Virus > ssRNA positive strand virus > SARS Coronavirus

    Signal Transduction > Protein Phosphorylation > Tyrosine Kinases

    亚基Interacts with JAKMIP1.
    组织特异性Observed in all cell lines analyzed. Expressed in a variety of lymphoid and non-lymphoid cell lines.
    相似性Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.
    Contains 1 FERM domain.
    Contains 2 protein kinase domains.
    Contains 1 SH2 domain.
    功能Probably involved in intracellular signal transduction by being involved in the initiation of type I IFN signaling. Phosphorylates the interferon-alpha/beta receptor alpha chain.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq].

     

     

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