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- Bioss
- bs-21956P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-21956P |
| 英文名称 | CHIA Antibody Blocking Peptide |
| 中文名称 | 哺乳动物酸性几丁质酶封闭多肽 |
| 英文别名 | CHIA; Acidic mammalian chitinase [Precursor]; CHIT2; chitinase, acidic; DKFZp313J1722; ECF L; RP5 1125M8.1; TSA1902. |
| 纯化方法 | HPLC |
| 研究领域 | Immunology > Immune System Diseases > Allergens Immunology > Innate Immunity > Cytokines > Interleukins Immunology > Innate Immunity > Macrophage / Inflamm. Microbiology > Organism > Eukaryotic Microorganism > Fungi > Cryptococcus neoformans Signal Transduction > Growth Factors/Hormones > EGF |
| 亚细胞定位 | Isoform 1: Secreted Isoforms 2 and 3: Cytoplasmic |
| 功能 | CHIA degrades chitin and chitotriose. May participate in the defense against nematodes and other pathogens. There are 3 named isoforms produced by alternative splicing. CHIA is induced via a T helper-2 (Th2)-specific, interleukin-13-mediated pathway in epithelial cells and macrophages. CHIA may be an important mediator of IL13-induced responses in Th2-dominated disorders such as asthma. CHIA hydrolysis N-acetyl-beta-D-glucosaminide 1,4-beta-linkages in chitin and chitodextrins. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene degrades chitin, which is found in the cell wall of most fungi as well as in arthropods and some nematodes. The encoded protein can also stimulate interleukin 13 expression, and variations in this gene can lead to asthma susceptibility. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Apr 2012] |
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CHIA Antibody Blocking Peptide(bs-21956P)-500ug
￥880
