- ￥880
- Bioss
- bs-11875P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-11875P |
| 英文名称 | PLPPR4 Antibody Blocking Peptide |
| 中文名称 | 脑特异性磷脂酸磷酸酶样蛋白1封闭多肽 |
| 英文别名 | Brain-specific phosphatidic acid phosphatase-like protein 1; KIAA0455; Lipid phosphate phosphatase-related protein type 4; Lppr4; LPPR4_HUMAN; Plasticity-related gene 1 protein; PRG-1. |
| 纯化方法 | HPLC |
| 亚细胞定位 | Membrane. |
| 组织特异性 | Specifically expressed in neurons. |
| 相似性 | Belongs to the PA-phosphatase related phosphoesterase family. |
| 功能 | Hydrolyzes lysophosphatidic acid (LPA). Facilitates axonal outgrowth during development and regenerative sprouting. In the outgrowing axons acts as an ecto-enzyme and attenuates phospholipid-induced axon collapse in neurons and facilitates outgrowth in the hippocampus. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Phosphatidate phosphatases are a family of integral membrane glycoproteins that dephosphorylate a variety of lipid phosphates and play a role in signal transduction via the phospholipase D pathway. PAP-2 proteins function independently of Mg2+ and are insensitive to NEM (N-ethylmaleimide) inhibition. The lipid phosphates degraded by this family include ceramide 1-phosphate (C1P), sphingosine 1-phosphate (S1P), phosphatidic acid (PA) and lysophosphatidic acid (LPA). LPPR4 (lipid phosphate phosphatase-related protein type 4), also known as LPR4, PHP1, PRG1 or PRG-1, is a 763 amino acid multi-pass membrane protein that belongs to the PA-phosphatase related phosphoesterase family. Exclusively expressed in neurons, LPPR4 hydrolyzes lysophosphatidic acid (LPA) and facilitates axonal outgrowth during development and regenerative sprouting. LPPR4 exists as two alternatively spliced isoforms and is encoded by a gene located on human chromosome 1p21.2. |
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PLPPR4 Antibody Blocking Peptide(bs-11875P)-500ug
￥880
