Recombinant human ICAM1 / CD54 protein, C-His(bs-10697P)-100ug/500ug/20ug

Recombinant human ICAM1 / CD54

protein, C-His(bs-10697P)-100ug/500ug/20ug
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  • ¥580 - 5680
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  • bs-10697P
  • 2025年10月16日
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      100ug/500ug/20ug

    规格:100ug产品价格:¥1880.0
    规格:500ug产品价格:¥5680.0
    规格:20ug产品价格:¥580.0
    产品编号bs-10697P
    英文名称Recombinant human ICAM1 / CD54 protein, C-His
    中文名称重组人细胞间粘附分子-1(CD54)蛋白
    英文别名BB2; CD54 antigen; CD54; ICAM1; ICAM 1; ICAM-1; Cell surface glycoprotein P3.58; Human rhinovirus receptor; Intercellular adhesion molecule 1; Major group rhinovirus receptor; MALA2; MyD10; P3.58; Surface antigen of activated B cells; ICAM1_HUMAN; MALA-2; MyD10; intercellular adhesion molecule 1 precursor; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor; major group rhinovirus receptor; Recombinant human ICAM1/CD54 protein, C-His
    性状Lyophilized or Liqui
    纯化方法AC
    理论分子量13.6
    实际分子量14 kDa
    浓度>0.5 mg/ml
    储存液10mM TBS (pH7.4).
    研究领域

    Cardiovascular > Angiogenesis > Endothelial Cell Markers

    Cardiovascular > Atherosclerosis > Vascular Inflammation > Leukocyte recruitment > Cell adhesion molecules

    Immunology > Adaptive Immunity > Regulatory T Cells

    Immunology > Cell Type Markers > CD > Adhesion

    Microbiology > Organism > Virus > RNA Virus > ssRNA positive strand virus > SARS Coronavirus

    Stem Cells > Hematopoietic Progenitors > Lymphoid > B Lymphocytic Lineage

    Stem Cells > Hematopoietic Progenitors > Lymphoid > T Lymphocytic Lineage

    亚基 Homodimer (Probable). Interacts with human herpesvirus 8 MIR2 protein (Probable). Interacts with MUC1 and promotes cell aggregation in epithelial cells. Interacts with ARHGEF26/SGEF. Binds to coxsackievirus A21 capsid proteins and acts as a receptor for this virus.
    亚细胞定位Membrane; Single-pass type I membrane protein.
    翻译后修饰Monoubiquitinated, which is promoted by MARCH9 and leads to endocytosis.
    相似性Belongs to the immunoglobulin superfamily. ICAM family.
    ontains 5 Ig-like C2-type (immunoglobulin-like) domains.
    功能 ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.
    保存条件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. [provided by RefSeq, Jul 2008].

     

     

    Recombinant human ICAM1 / CD54
    The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.

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