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- 规格:
100ug/500ug/20ug
| 规格: | 100ug | 产品价格: | ¥1880.0 |
|---|---|---|---|
| 规格: | 500ug | 产品价格: | ¥5680.0 |
| 规格: | 20ug | 产品价格: | ¥580.0 |
| 产品编号 | bs-10697P |
| 英文名称 | Recombinant human ICAM1 / CD54 protein, C-His |
| 中文名称 | 重组人细胞间粘附分子-1(CD54)蛋白 |
| 英文别名 | BB2; CD54 antigen; CD54; ICAM1; ICAM 1; ICAM-1; Cell surface glycoprotein P3.58; Human rhinovirus receptor; Intercellular adhesion molecule 1; Major group rhinovirus receptor; MALA2; MyD10; P3.58; Surface antigen of activated B cells; ICAM1_HUMAN; MALA-2; MyD10; intercellular adhesion molecule 1 precursor; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor; major group rhinovirus receptor; Recombinant human ICAM1/CD54 protein, C-His |
| 性状 | Lyophilized or Liqui |
| 纯化方法 | AC |
| 理论分子量 | 13.6 |
| 实际分子量 | 14 kDa |
| 浓度 | >0.5 mg/ml |
| 储存液 | 10mM TBS (pH7.4). |
| 研究领域 | Cardiovascular > Angiogenesis > Endothelial Cell Markers Cardiovascular > Atherosclerosis > Vascular Inflammation > Leukocyte recruitment > Cell adhesion molecules Immunology > Adaptive Immunity > Regulatory T Cells Immunology > Cell Type Markers > CD > Adhesion Microbiology > Organism > Virus > RNA Virus > ssRNA positive strand virus > SARS Coronavirus Stem Cells > Hematopoietic Progenitors > Lymphoid > B Lymphocytic Lineage Stem Cells > Hematopoietic Progenitors > Lymphoid > T Lymphocytic Lineage |
| 亚基 | Homodimer (Probable). Interacts with human herpesvirus 8 MIR2 protein (Probable). Interacts with MUC1 and promotes cell aggregation in epithelial cells. Interacts with ARHGEF26/SGEF. Binds to coxsackievirus A21 capsid proteins and acts as a receptor for this virus. |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein. |
| 翻译后修饰 | Monoubiquitinated, which is promoted by MARCH9 and leads to endocytosis. |
| 相似性 | Belongs to the immunoglobulin superfamily. ICAM family. ontains 5 Ig-like C2-type (immunoglobulin-like) domains. |
| 功能 | ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus. |
| 保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. [provided by RefSeq, Jul 2008]. |

The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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Recombinant human ICAM1 / CD54 protein, C-His(bs-10697P)-100ug/500ug/20ug
¥580 - 5680







