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- Bioss
- bs-17123P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-17123P |
| 英文名称 | TRIM68 Antibody Blocking Peptide |
| 中文名称 | TRIM68蛋白封闭多肽 |
| 英文别名 | E3 ubiquitin-protein ligase TRIM68; FLJ10369; GC109; MGC126176; RING finger protein 137; RNF 137; RNF137; Ro/SSA1 related protein; SS 56; SS-56; SS56; SSA protein SS 56; SSA protein SS-56; TRI68_HUMAN; TRIM 68; Trim68; Tripartite motif containing 68; Tripartite motif containing protein 68; Tripartite motif-containing protein 68. |
| 纯化方法 | HPLC |
| 亚基 | Interacts with AR/androgen receptor (via ligand-binding domain). Interacts with KAT5/TIP60. |
| 亚细胞定位 | Cytoplasm > perinuclear region. Nucleus. Colocalized with AR in nucleus. |
| 组织特异性 | Widely expressed. Expressed at high levels in prostate cancer cell lines. Up-regulation could be restricted to androgen-dependent cells. |
| 翻译后修饰 | Auto-ubiquitinated. |
| 相似性 | Belongs to the TRIM/RBCC family. Contains 1 B box-type zinc finger. Contains 1 B30.2/SPRY domain. Contains 1 RING-type zinc finger. |
| 功能 | Functions as an ubiquitin E3 ligase. Acts as a coactivator of androgen receptor (AR) depending on its ubiquitin ligase activity. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a protein which contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. This gene is expressed in many cancer cell lines. Its expression in normal tissues, however, was found to be restricted to prostate. This gene was also found to be differentially expressed in androgen-dependent versus androgen-independent prostate cancer cells. [provided by RefSeq, Oct 2011] |
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TRIM68 Antibody Blocking Peptide(bs-17123P)-500ug
￥880
