DDC Antibody Blocking Peptide(bs-0180P)-500ug

DDC Antibody Blocking Peptide(

bs-0180P)-500ug
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  • ¥880
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  • bs-0180P
  • 2025年10月16日
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      500ug

    产品编号bs-0180P
    英文名称DDC Antibody Blocking Peptide
    中文名称多巴胺脱羧酶封闭多肽
    英文别名AADC; DDC; Aromatic L Amino Acid Decarboxylase; DDC protein; DOPA decarboxylase; aromatic-L-amino-acid decarboxylase isoform 1; DDC_HUMAN.
    性状Lyophilized
    纯化方法HPLC
    研究领域

    Cancer > Cancer Metabolism > Metabolic signaling pathway > Hormone biosynthesis

    Metabolism > Pathways and Processes > Endocrine metabolism > Hormone biosynthesis

    Neuroscience > Neurotransmitter > Biogenic Amines > Dopamine

    亚基Homodimer.
    相似性Belongs to the group II decarboxylase family.
    功能Catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    背景资料bs-0180P is one synthetic peptide derived from human DDC. DOPA decarboxylase is an enzyme implicated in 2 metabolic pathways, synthesizing 2 important neurotransmitters: dopamine and serotonin which both play key roles in many clinical disorders, including Parkinson's disease. Following the hydroxylation of tyrosine to form L dihydroxyphenylalanine (LDOPA), catalyzed by tyrosine hydroxylase, DDC decarboxylates LDOPA to form dopamine. This neurotransmitter is found in different areas of the brain and is particularly abundant in basal ganglia. Dopamine is also produced by DDC in the sympathetic nervous system and is the precursor of the catecholaminergic hormones, noradrenaline and adrenaline in the adrenal medulla. In the nervous system, tryptophan hydroxylase produces 5 OH tryptophan, which is decarboxylated by DDC, giving rise to serotonin. DDC is a homodimeric, pyridoxal phosphate dependent enzyme.

     

     

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