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- 2025年10月16日
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500ug
| 产品编号 | bs-11865P |
| 英文名称 | KLF7 Antibody Blocking Peptide |
| 中文名称 | KLF样转录因子7封闭多肽 |
| 英文别名 | KLF7; KLF7_HUMAN; Krueppel like factor 7; Krueppel-like factor 7; Kruppel like factor 7 ; Ubiquitous krueppel like factor; Ubiquitous krueppel-like factor; UKLF. |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > Transcription > Domain Families > Krueppel like factor Epigenetics and Nuclear Signaling > Transcription > Krueppel like factor Epigenetics and Nuclear Signaling > Transcription > Other factors Epigenetics and Nuclear Signaling > Transcription > Polymerase associated factors > Pol II Transcription Epigenetics and Nuclear Signaling > Transcription > Transcription Factors Neuroscience > Neurology process > Neurogenesis |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Ubiquitous and highly expressed in brain and spinal cord in the adult, and in kidney and brain in the embryo. |
| 相似性 | Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 3 C2H2-type zinc fingers. |
| 功能 | Transcriptional activator. Binds in vitro to the CACCC motif of the beta-globin promoter and to the SP1 recognition sequence. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | KLF7 is a transcriptional activator that belongs to the Krüppel C2H2-type zinc finger protein family. KLF7 targets promotor regions bearing CACCC elements in order to regulate transcription. It is believed that KLF7 is an important element for regulation of differentiation and the development of nervous systems. Specifically, increased expression of KLF7 is associated with neuronal precursors exiting the cell cycle and beginning to differentiate. Overexpression of KLF7 can lead to cell cycle arrest and a decrease in DNA synthesis. Also, KLF7 is thought to regulate the expression of Trk A, the receptor for nerve growth factor, which is required for the normal growth and maturation of neurons. KLF7 is a widely expressed protein with highest expression found in brain and nervous tissue. |
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文献和实验or from the literature are missing. In this article, processing parameters for DNA, peptide, antibody, and carbohydrate microarrays are outlined. The applicability of the model experiments is demonstrated and described in detail on the example of short oligonucleotides.
Synthesis and Probing of Membrane-bound Peptide Arrays
the stringency of the blocking conditions and make sure that the primary binding partner and detection reagent (e.g., antibody) are of high purity and are used in the highest possible dilution. Stage
Mapping Protein‐Protein Interactions with Phage‐Displayed Combinatorial Peptide Libraries
. Fack, F., Deroo, S., Kreis, S., and Muller, C.P. 2000. Heteroduplex mobility assay (HMA) pre‐screening: An improved strategy for the rapid identification of inserts selected from phage‐displayed peptide
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