FATE1 Antibody Blocking Peptide(bs-16029P)-500ug

FATE1 Antibody Blocking Peptid

e(bs-16029P)-500ug
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  • ¥880
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  • bs-16029P
  • 2025年10月16日
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      500ug

    产品编号bs-16029P
    英文名称FATE1 Antibody Blocking Peptide
    中文名称FATE1蛋白封闭多肽
    英文别名Cancer/testis antigen 43; CT43; FATE; FATE1; FATE1_HUMAN; fetal and adult testis expressed 1; fetal and adult testis expressed transcript protein; Fetal and adult testis-expressed transcript protein; Protein BJ HCC 2; Tumor antigen BJ-HCC-2.
    纯化方法HPLC
    研究领域

    Cancer > Tumor immunology > Tumor-associated antigens

    亚细胞定位Membrane.
    组织特异性Testis-specific in fetus (aged from 6 to 11 weeks). In adult, expressed predominantly in testis, with some expression in lung, heart, kidney, adrenal gland and whole brain.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料FATE1 (fetal and adult testis expressed 1), also known as FATE, CT43 (cancer/testis antigen 43) or BJ-HCC-2, is a cancer/testis antigen found in testis and tumor tissues (specifically hepatocarcinoma cells). Its expression is regulated by SF-1 (Steroidogenic Factor 1) and WT1 (Wilms’ tumor protein), two proteins involved in tumorigenesis, suggesting a role for FATE1 in tumor development. FATE1 is exclusively expressed in testis of the 6-11 week old fetus (around the period of gonadal sex differentiation). At 7 weeks, FATE1 is coexpressed with SRY and may play a role in early testicular differentiation. In adults, although predominantly expressed in testis, FATE1 can also be found in heart, kidney, brain, lung and adrenal gland. Mutations in the gene encoding FATE1 may be contributing factors in male infertility.

     

     

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