- ￥880
- Bioss
- bs-21929P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-21929P |
| 英文名称 | PTN Antibody Blocking Peptide |
| 中文名称 | 多效生长因子封闭多肽 |
| 英文别名 | pleiotrophin; HARP; HBBM; HBGAM; HBGF8; HBNF; HBNF1; Heparin Binding Growth Factor 8; Heparin binding neurite outgrowth promoting factor 1; heparin-binding growth associated molecule; NEGF1; Neurite Growth Promoting Factor 1; OSF-1; osteoblast-specific factor; PTN; PTN_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Growth factors > Hormones Immunology > Innate Immunity > Cytokines Neuroscience > Neurology process > Growth and Development > Neurotrophins Signal Transduction > Cytoskeleton / ECM > Extracellular Matrix > Structures > Bone |
| 亚基 | Interacts with ALK and NEK6. |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Osteoblast and brain. |
| 翻译后修饰 | Phosphorylated by NEK6. |
| 相似性 | Belongs to the pleiotrophin family. |
| 功能 | Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells. Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti-apoptotic signaling of PTN and regulation of cell proliferation. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Pleiotrophin is a heparin-binding growth factor involved in the differentiation and proliferation of neuronal tissue during embryogenesis, and also secreted by melanoma and breast carcinoma cells. Pleiotrophin exhibits mitogenic and angiogenic properties and has been shown to influence the vascular supply, expansion and metastasis of tumour cells. |
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PTN Antibody Blocking Peptide(bs-21929P)-500ug
￥880
