FAM83G Antibody Blocking Peptide(bs-16017P)-500ug

FAM83G Antibody Blocking Pepti

de(bs-16017P)-500ug
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  • ¥880
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  • bs-16017P
  • 2025年10月16日
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      500ug

    产品编号bs-16017P
    英文名称FAM83G Antibody Blocking Peptide
    中文名称FAM83G蛋白封闭多肽
    英文别名FA83G_HUMAN; Fam83g; Family with sequence similarity 83, member G; Protein FAM83G.
    纯化方法HPLC
    研究领域

    Cell Biology > Other Antibodies > Other Antibodies

    相似性Belongs to the FAM83 family.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Chromosome 17 makes up over 2.5% of the human genome with about 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17. The FAM83G gene product has been provisionally designated FAM83G pending further characterization.

     

     

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