- ￥880
- Bioss
- bs-2730P
- 2025年10月16日
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- 规格：
500ug
| 产品编号 | bs-2730P |
| 英文名称 | ULBP3/N2DL3; Antibody Blocking Peptide |
| 中文名称 | UL16结合蛋白3封闭多肽 |
| 英文别名 | ALCAN-gamma; N2DL-3; N2DL3; NKG2D ligand 3; NKG2D ligand 3 precursor; NKG2DL3; OTTHUMP00000017411; RAET1N; Retinoic acid early transcript 1N; UL16 binding protein 3; UL16-binding protein 3; N2DL3_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Immunology > Innate Immunity > NK Cells |
| 亚基 | Does not interact with the CMV glycoprotein UL16. Does not bind to beta2-microglobulin. |
| 亚细胞定位 | Cell membrane; Lipid-anchor, GPI-anchor. |
| 相似性 | Belongs to the MHC class I family. |
| 功能 | Ligand for the NKG2D receptor, together with at least ULBP1 and ULBP2. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. Has lower affinity for NKG2D compared to ULBP1 and ULBP2 and induces weaker signaling responses than does ULBP2 or ULBP1. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | ULBP3 is a human ligand for the NKG2D receptor, together with at least ULBP1 and ULBP2. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. ULBP3 has a lower affinity for NKG2D compared to ULBP1 and ULBP2 and induces weaker signaling responses than does ULBP2 or ULBP1. |
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ULBP3/N2DL3; Antibody Blocking Peptide(bs-2730P)-500ug
￥880
