TPSAB1 | Mast Cell Tryptase Ab Blocking Peptide(bs-2725P)-500ug产品图

TPSAB1 | Mast Cell Tryptase Ab

Blocking Peptide(bs-2725P)-500ug
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  • bs-2725P
  • 2026年10月10日
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    • 规格:

      500ug

    产品编号bs-2725P
    英文名称TPSAB1 Antibody Blocking Peptide
    中文名称肥大细胞类胰蛋白酶封闭多肽
    英文别名Tryptase delta; Delta-tryptase; HmMCP-3-like tryptase III; Mast cell mMCP-7-like; Tryptase-3; TPSD1; MCP7L1; MMCP-7L; MCP7-LIKE; EC 3.4.21.59; MGC95428; TRYD; Tryptase3; alpha II; EC 3.4.21.59; Lung tryptase; Mast cell alpha II tryptase; Mast cell beta I tryptase; Mast cell protease 7; Mast cell protease II; MCP 7; MMCP 7; Pituitary tryptase; Skin tryptase; TPS 1; TPS1; TPS2; TPSAB1; TPSAB1 protein; TPSB1; Tryptase 1; Tryptase alpha 1; tryptase alpha I included; Tryptase alpha II; tryptase alpha II included; tryptase alpha included; tryptase alpha/beta 1; Tryptase beta 1; tryptase beta I included; Tryptase I; tryptase I included; Tryptase III; Tryptase skin; Tryptase beta-2; TRYB1_HUMAN; TRYB2_HUMAN; TRYD_HUMAN.
    纯化方法HPLC
    研究领域

    Immunology > Innate Immunity > Macrophage / Inflamm.

    Metabolism > Pathways and Processes > Metabolic signaling pathways > Amino acid metabolism

    Metabolism > Types of disease > Cancer

    Signal Transduction > Metabolism > Amino Acids

    亚基Homotetramer.
    亚细胞定位Secreted. Note=Released from the secretory granules upon mast cell activation.
    组织特异性Expressed in colon, lung, heart and synovial tissue. May be specific to mast cells.
    相似性Belongs to the peptidase S1 family. Tryptase subfamily._x000D_
    Contains 1 peptidase S1 domain.
    功能Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. Although this gene may be an exception, most of the tryptase genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. This gene was once considered to be a pseudogene, although it is now believed to be a functional gene that encodes a protein. [provided by RefSeq, Jul 2008]

     

     

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