phospho-alpha Adducin (Ser436) Antibody Blocking Peptide(bs-15968P)-500ug

phospho-alpha Adducin (Ser436)

Antibody Blocking Peptide(bs-15968P)-500ug
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  • ¥1080
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  • bs-15968P
  • 2025年10月16日
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      500ug

    产品编号bs-15968P
    英文名称phospho-alpha Adducin (Ser436) Antibody Blocking Peptide
    中文名称磷酸化内收蛋白a1封闭多肽
    英文别名alpha Adducin(phospho S436); alpha Adducin(phospho Ser436); p-alpha Adducin(S436); p-alpha Adducin(Ser436); ADD 1; ADD A; ADD1; ADD1 protein; ADDA; ADDA_HUMAN; Adducin 1 (alpha); Adducin 1 alpha; Alpha adducin; Alpha-adducin; Erythrocyte adducin alpha subunit; Erythrocyte hosphor subunit alpha; Erythrocyte adducin subunit alpha.
    纯化方法HPLC
    研究领域

    Signal Transduction > Protein Phosphorylation > Ser / Thr Kinases > PKA

    Signal Transduction > Protein Phosphorylation > Ser / Thr Kinases > PKC

    Signal Transduction > Signaling Pathway > Calcium Signaling > Calmodulin Pathway

    Tags & Cell Markers > Subcellular Markers > Cytoskeleton > Actin

    亚基Heterodimer of an alpha and a beta subunit or an alpha and a gamma subunit.
    亚细胞定位Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
    组织特异性Expressed in all tissues. Found in much higher levels in reticulocytes than the beta subunit.
    相似性Belongs to the aldolase class II family. Adducin subfamily.
    功能Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to calmodulin.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Adducins are a family of cytoskeleton proteins encoded by three genes (Alpha, Beta, Gamma). Adducin is a protein associated with the inner leaflet of the plasma membrane and is one of the proteins localized at the spectrin-actin junction of the membrane skeleton. The cortical actin cytoskeletal network is lost during apoptosis and Adducins are central in the cortical actin network organization. Adducin Alpha is a cytoskeletal protein involved with sodium-pump activity in the renal tubule and is associated with hypertension. The expression of Adducin Alpha and Adducin Gamma is ubiquitous in contrast to the restricted expression of Adducin Beta. Adducin Beta is expressed at high levels in brain and hematopoietic tissues, such as bone marrow, in humans, and in spleen in mice.

     

     

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