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- Bioss
- bs-11838P
- 2025年10月16日
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500ug
| 产品编号 | bs-11838P |
| 英文名称 | Emx1 Antibody Blocking Peptide |
| 中文名称 | 有脊椎动物脑发育相关蛋白Emx1封闭多肽 |
| 英文别名 | Empty spiracles homeobox 1; Empty spiracles homolog 1; empty spiracles homolog 1 Drosophila antibodyEmpty spiracles like protein 1; Empty spiracles-like protein 1; EMX1 ; EMX1_HUMAN ; Homeobox protein EMX1. |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > Transcription > Domain Families > Developmental Families > HOX Neuroscience > Neurology process > Neurogenesis Stem Cells > Neural Stem Cells > Intracellular |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Cerebral cortex. |
| 相似性 | Belongs to the EMX homeobox family. Contains 1 homeobox DNA-binding domain. |
| 功能 | Transcription factor, which in cooperation with EMX2, acts to generate the boundary between the roof and archipallium in the developing brain. May function in combinations with OTX1/2 to specify cell fates in the developing central nervous system. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Emx1 and Emx2 are human homologs to the Drosophila developmental genes empty spiracles expressed in anterior body regions during early Drosophila embryogenesis. Emx1 and Emx2 are homeobox proteins expressed in the developing vertebrate brain. Emx2 is expressed in the dorsal telencephalon and small diencephalic regions, while Emx1 expression is exclusively confined to pyramidal neurons of the dorsal telencephalon. In the embryonic brain, Emx1 is expressed in both proliferating and differentiating neurons while Emx2 is expressed only in proliferating neurons. OTX1 and OTX2 are human homologs of the Drosophila developmental genes orthodenticle. In development, the sequence of expression begins with OTX2 at day 10 post coitum followed by OTX1, Emx2 and finally Emx1. The genes encoding human Emx1 and Emx2 map to chromosomes 2p14-p13 and 10q26.1, respectively. |
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Emx1 Antibody Blocking Peptide(bs-11838P)-500ug
￥880
