- ￥880
- Bioss
- bs-1586P
- 2025年10月16日
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- 技术资料
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500ug
| 产品编号 | bs-1586P |
| 英文名称 | VEGF-C Antibody Blocking Peptide |
| 中文名称 | 血管内皮生长因子C型封闭多肽 |
| 英文别名 | Vascuoar endothelial growth factor-C; AW228853; Flt4 ligand; Flt4-L; VEGF2; VEGFC; VRP; VEGFC_HUMAN. |
| 性状 | Lyophilized |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Growth factors > VEGF Cancer > Invasion/microenvironment > Angiogenesis > Angiogenic growth factors Cardiovascular > Angiogenesis > Growth Factors > VEGF > VEGF Neuroscience > Neurology process > Neurogenesis Signal Transduction > Growth Factors/Hormones > VEGF |
| 亚基 | Homodimer; non-covalent and antiparallel. |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Spleen, lymph node, thymus, appendix, bone marrow, heart, placenta, ovary, skeletal muscle, prostate, testis, colon and small intestine and fetal liver, lung and kidney, but not in peripheral blood lymphocyte. |
| 相似性 | Belongs to the PDGF/VEGF growth factor family. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | Vascular endothelial growth factors (VEGFs), also known as vasculotropins, are a family of closely related growth factors having a conserved pattern of eight cysteine residues and sharing common VEGF receptors. VEGFs stimulate the proliferation of endothelial cells, induce angiogenesis, promote cell migration, increase vascular permeability, and inhibit apoptosis. The mitogenic activity of VEGFs appears to be mediated by specific VEGF receptors. The target cell specificity of VEGF is restricted to vascular endothelial cells. Vascular Endothelial Growth Factor C (VEGFC) is a member of the VEGF subfamily of PDGF-related growth factors. It is the ligand for Flt4 (VEGFR3) and KDR (VEGFR2). VEGFC binds Flt4 and induces tyrosine autophosphorylation of VEGFR3 and VEGFR2. VEGFC also stimulates the migration of bovine capillary endothelial cells in collagen gel. It is a specific growth factor for the lymphatic vascular system and mediates lymphangiogenesis. VEGFC is abundantly expressed in heart and skeletal muscle. Other tissues such as lung and kidney also express VEGFC. |
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VEGF-C Antibody Blocking Peptide(bs-1586P)-500ug
￥880
