SLAMF6 Antibody Blocking Peptide(bs-2682P)-500ug

SLAMF6 Antibody Blocking Pepti

de(bs-2682P)-500ug
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  • ¥880
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  • bs-2682P
  • 2025年10月16日
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      500ug

    产品编号bs-2682P
    英文名称SLAMF6 Antibody Blocking Peptide
    中文名称SLAMF6封闭多肽
    英文别名LY108; Activating NK receptor; KALI; KALIb; MGC104953; NK T B antigen; NTB A; NTBA; SF2000; SLAM family member 6; SLAM family member 6 precursor; SLAMF6; SLAF6_HUMAN; NK-T-B-antigen; NTB-A; CD352.
    纯化方法HPLC
    研究领域

    Immunology > Cell Type Markers > CD > NK Cells

    亚基Homodimer. Interacts with PTN6 and, upon phosphorylation, with PTN11 and SH2D1A/SAP.
    亚细胞定位Cell membrane; Single-pass type I membrane protein (Probable).
    组织特异性Expressed by all (resting and activated) natural killer cells (NK), T- and B-lymphocytes.
    相似性Contains 1 Ig-like (immunoglobulin-like) domain.
    功能Triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料SLAMF6 is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. SLAMF6 is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It may function as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. It may play a role in the regulation of autoimmune diseases.

     

     

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