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500ug
| 产品编号 | bs-2682P |
| 英文名称 | SLAMF6 Antibody Blocking Peptide |
| 中文名称 | SLAMF6封闭多肽 |
| 英文别名 | LY108; Activating NK receptor; KALI; KALIb; MGC104953; NK T B antigen; NTB A; NTBA; SF2000; SLAM family member 6; SLAM family member 6 precursor; SLAMF6; SLAF6_HUMAN; NK-T-B-antigen; NTB-A; CD352. |
| 纯化方法 | HPLC |
| 研究领域 | Immunology > Cell Type Markers > CD > NK Cells |
| 亚基 | Homodimer. Interacts with PTN6 and, upon phosphorylation, with PTN11 and SH2D1A/SAP. |
| 亚细胞定位 | Cell membrane; Single-pass type I membrane protein (Probable). |
| 组织特异性 | Expressed by all (resting and activated) natural killer cells (NK), T- and B-lymphocytes. |
| 相似性 | Contains 1 Ig-like (immunoglobulin-like) domain. |
| 功能 | Triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | SLAMF6 is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. SLAMF6 is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It may function as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. It may play a role in the regulation of autoimmune diseases. |
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SLAMF6 Antibody Blocking Peptide(bs-2682P)-500ug
¥880







