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- Bioss
- bs-21796P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-21796P |
| 英文名称 | Neuroligin 1 Antibody Blocking Peptide |
| 中文名称 | 突触细胞粘附分子1封闭多肽 |
| 英文别名 | NLG 1; KIAA1070; MGC45115; NLG1; Neuroligin-1; NLGN1; NLGN1_HUMAN. |
| 纯化方法 | HPLC |
| 亚基 | Interacts with NRXN1, NRXN2 and NRXN3. Interacts with NLGN3. Interacts with AIP1 and PDZRN3. Interacts (via its C-terminus) with DLG4/PSD-95 (via PDZ domain 3). Interacts with GOPC. |
| 亚细胞定位 | Cell membrane; Single-pass type I membrane protein. Cell junction, synapse. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Note=Enriched in synaptic plasma membranes and clustered in synaptic clefts and postsynaptic densities. Detected at dendritic spines. Colocalized with DLG4/PSD-95 and GRIN1/NMDAR1. |
| 组织特异性 | Expressed in the blood vessel walls (at protein level). Detected in brain, and at lower levels in pancreas islet beta cells. |
| 翻译后修饰 | Belongs to the type-B carboxylesterase/lipase family. |
| 相似性 | Belongs to the type-B carboxylesterase/lipase family. |
| 功能 | Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. In vitro, triggers the de novo formation of presynaptic structures. May be involved in specification of excitatory synapses. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Neuroligin 1 is a synaptic cell-adhesion molecule that is enriched in postsynaptic densities where it may recruit receptors, channels, and signal-transduction molecules to synaptic sites of cell adhesion. In addition, the neuroligin/beta-neurexin junction may be involved in the excitatory/inhibitory specification of CNS neuron synapses. A role for Neuroligin 1 is also suggested in autism. |
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Neuroligin 1 Antibody Blocking Peptide(bs-21796P)-500ug
￥880
