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- bs-3223P
- 2025年10月16日
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- 规格：
500ug
| 产品编号 | bs-3223P |
| 英文名称 | Phospho-HSL (Ser863) Antibody Blocking Peptide |
| 中文名称 | 磷酸化荷尔蒙敏感脂肪酶封闭多肽 |
| 英文别名 | Hormone sensitive lipase; Hormone sensitive lipase testicular isoform; HSL; LHS; Lipase hormone sensitive; LIPE. |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Cancer Metabolism > Metabolic signaling pathway > Metabolism of lipids and lipoproteins Cardiovascular > Lipids / Lipoproteins > Lipid Metabolism > Cholesterol Metabolism Cardiovascular > Lipids / Lipoproteins > Lipid Metabolism > Lipases Metabolism > Pathways and Processes > Metabolic signaling pathways > Lipid and lipoprotein metabolism > Cholesterol Metabolism Metabolism > Pathways and Processes > Metabolic signaling pathways > Lipid and lipoprotein metabolism > Lipases Metabolism > Pathways and Processes > Metabolic signaling pathways > Lipid and lipoprotein metabolism > Lipid metabolism Metabolism > Types of disease > Cancer Signal Transduction > Metabolism > Lipid metabolism |
| 亚基 | Interacts with PTRF in the adipocyte cytoplasm. |
| 亚细胞定位 | Cell membrane. Membrane, caveola. Cytoplasm,bcytosol. Note=Found in the high-density caveolae. Translocates to the cytoplasm from the caveolae upon insulin stimulation. |
| 翻译后修饰 | Phosphorylation by AMPK may block translocation to lipid droplets. |
| 相似性 | Belongs to the 'GDXG' lipolytic enzyme family. |
| 功能 | In adipose tissue and heart, it primarily hydrolyzes stored triglycerides to free fatty acids, while in steroidogenic tissues, it principally converts cholesteryl esters to free cholesterol for steroid hormone production. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | HSL/LIPE is found in adipose tissue and heart, where it primarily hydrolyzes stored triglycerides to free fatty acids. It is also found in steroidogenic tissues, where it principally converts cholesteryl esters to free cholesterol for steroid hormone production. There are two named isoforms. |
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