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500ug
| 产品编号 | bs-11828P |
| 英文名称 | CTDNEP1 Antibody Blocking Peptide |
| 中文名称 | DULLARD蛋白封闭多肽 |
| 英文别名 | Dullard homolog; HSA 011916; NET 56 antibodySerine threonine protein phosphatase dullard; CNEP1_HUMAN. |
| 纯化方法 | HPLC |
| 亚基 | Interacts with CNEP1R1; the complex dephosphorylates LPIN1 and LPIN2. |
| 亚细胞定位 | Endoplasmic reticulum membrane; Single-pass membrane protein. Nuclear membrane; Single-pass membrane protein. |
| 组织特异性 | Muscle specific with lower expression in other metabolic tissues. |
| 相似性 | Belongs to the dullard family. Contains 1 FCP1 homology domain. |
| 功能 | DULLARD is a serine/threonine phosphatase which may be required for proper nuclear membrane morphology. It is involved in LPIN1 dephosphorylation and may antagonize BMP signaling. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. Dullard, also known as NET56, is a 244 amino acid single-pass membrane protein that localizes to both the nucleus and the endoplasmic reticulum and contains one FCP1 homology domain. Functioning as a serine/threonine phosphatase, Dullard catalyses the dephosphorylation of target proteins and is thought to be required for proper nuclear membrane morphology. Human Dullard shares 92% sequence identity with its zebrafish counterpart, suggesting a conserved role between species. |
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CTDNEP1 Antibody Blocking Peptide(bs-11828P)-500ug
¥880







