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- Bioss
- bs-2654P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-2654P |
| 英文名称 | LTB4R Antibody Blocking Peptide |
| 中文名称 | 白三烯B4受体1封闭多肽 |
| 英文别名 | Leukotriene B4 receptor 1; Leukotriene B4 receptor; BLT; BLT1; BLTR; Chemokine receptor like 1; CMKRL1; G protein coupled receptor 16; GPR16; Leukotriene B4 G Protein coupled receptor; LTB4 R 1; LTB4R 1; LTB4R; LTBR1; P2RY7; P2Y purinoceptor 7; P2Y7; Purinergic receptor P2Y G protein coupled 7; LT4R1_HUMAN; LTB4-R 1; LTB4-R1; Chemoattractant receptor-like 1; G-protein coupled receptor 16; P2Y purinoceptor 7; P2Y7. |
| 纯化方法 | HPLC |
| 研究领域 | Cardiovascular > Atherosclerosis > Lipoprotein metabolism Cardiovascular > Blood Immunology > Innate Immunity > Macrophage / Inflamm. Metabolism > Pathways and Processes > Metabolic signaling pathways > Lipid and lipoprotein metabolism > Lipoprotein metabolism Metabolism > Types of disease > Heart disease Signal Transduction > Signaling Pathway > G Protein Signaling > GPCR Signal Transduction > Signaling Pathway > Lipid Signaling |
| 亚细胞定位 | Cell membrane; Multi-pass membrane protein. |
| 组织特异性 | Expressed at highest levels in heart, skeletal muscle and at lower levels in brain and liver. High level of expression in lymphoid tissues. |
| 翻译后修饰 | Phosphorylated by GRK6 upon leukotriene B4 binding; which promotes desensitization. |
| 相似性 | Belongs to the G-protein coupled receptor 1 family. |
| 功能 | Receptor for extracellular ATP, UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Leukotriene B4 Receptor is a member of the GPCR family (subfamily:chemoattractant). It is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response. It has been reported in blood, bone marrow, brain, heart, liver, and skeletal muscle. In addition, it has been shown to be highly expressed in leukocytes and lymphoid tissues such as spleen, thymus, and lymph node. ESTs have been isolated from B cell/lung/testis, breast, colon, eye, kidney, skin, spleen, testis, and tonsil libraries. |
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LTB4R Antibody Blocking Peptide(bs-2654P)-500ug
￥880
