ADCY3 Antibody Blocking Peptide(bs-20272P)-500ug

ADCY3 Antibody Blocking Peptid

e(bs-20272P)-500ug
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  • ¥800
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  • bs-20272P
  • 2025年10月16日
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      500ug

    产品编号bs-20272P
    英文名称ADCY3 Antibody Blocking Peptide
    中文名称腺苷酸环化酶3封闭多肽
    英文别名A cyclase III; AC3; adenylate cyclase 3; Adenylate cyclase type III; ADCY3_HUMAN; Adenylate cyclase type 3; ATP pyrophosphate-lyase 3; AC-III; Adenylate cyclase, olfactive type; AC3.
    性状Lyophilized
    纯化方法HPLC
    研究领域

    Cancer > Cancer Metabolism > Metabolic signaling pathway > Integration of energy metabolism

    Metabolism > Pathways and Processes > Metabolic signaling pathways > Energy transfer pathways > Integration of energy

    Metabolism > Types of disease > Cancer

    Signal Transduction > Signaling Pathway > G Protein Signaling > GPCR

    亚细胞定位Membrane; Multi-pass membrane protein.
    组织特异性Expressed in brain, heart, kidney, liver, lung, pancreas, placenta, and skeletal muscle.
    相似性Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
    Contains 2 guanylate cyclase domains.
    功能Mediates odorant detection (possibly) via modulation of intracellular cAMP concentration.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The cAMP synthesizing enzymes are found in two forms: cytosolic (soluble) and membrane-bound (particulate). Stimulation of adenylate cyclases produce cAMP form ATP in response to the activation of GPCRs by various hormones, neurotransmitters and other regulatory molecules. cAMP, in subsequent steps down the signal transduction pathway, can stimulate cAMP-dependent protein kinase A (cPKA), and several other target molecules. Activation of cPKA can phosphorylate a broad range of substrates that regulate various metabolic pathways, gene expression, and affect memory functions etc. The stimulation of adenylate cyclases starts with interactions with GPCRs mediated signals initiated by Gs and Gi heterotrimeric G-proteins.

     

     

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