RAMP-1 Antibody Blocking Peptide(bs-1567P)-500ug

RAMP-1 Antibody Blocking Pepti

de(bs-1567P)-500ug
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  • bs-1567P
  • 2025年10月16日
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      500ug

    产品编号bs-1567P
    英文名称RAMP-1 Antibody Blocking Peptide
    中文名称受体活性修饰蛋白1封闭多肽
    英文别名calcitonin receptor like receptor activity modifying protein 1; RAMP 1; RAMP-1; CRLR activity modifying protein 1; receptor (G protein coupled) activity modifying protein 1; receptor activity modifying protein 1; Receptor activity modifying protein 1; RAMP1_HUMAN.
    纯化方法HPLC
    研究领域

    Neuroscience > Neurotransmission > Receptors / Channels > GPCR > More GPCR

    Neuroscience > Neurotransmitter > Neuropeptides > More Neuropeptides

    Signal Transduction > Signaling Pathway > G Protein Signaling > GPCR

    亚基Heterodimer of CALCRL and RAMP1.
    亚细胞定位Membrane; Single-pass type I membrane protein.
    组织特异性Expressed in many tissues including the uterus, bladder, brain, pancreas and gastro-intestinal tract.
    相似性Belongs to the RAMP family.
    功能Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. Acts as a receptor for calcitonin-gene-related peptide (CGRP) together with CALCRL.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The protein encoded by this gene is a member of the RAMP family of single transmembrane domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin receptor like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin gene related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface.

     

     

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