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- Bioss
- bs-13067P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-13067P |
| 英文名称 | ELK4 Antibody Blocking Peptide |
| 中文名称 | 血清反应因子辅助蛋白1封闭多肽 |
| 英文别名 | Elk4; ELK4_HUMAN; ETS domain containing protein Elk4; ETS domain protein; ETS domain-containing protein Elk-4; SAP-1; SAP1; Serum response factor accessory protein 1; SRF accessory protein 1; TCF1. |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > Transcription > Cancer susceptibility > Proto-oncogenes Epigenetics and Nuclear Signaling > Transcription > Domain Families > Ets |
| 亚基 | Interacts with SIRT7. |
| 亚细胞定位 | Nucleus. |
| 相似性 | Belongs to the ETS family. Contains 1 ETS DNA-binding domain. |
| 功能 | Forms a ternary complex with the serum response factor (SRF). Requires DNA-bound SRF for ternary complex formation and makes extensive DNA contacts to the 5'side of SRF, but does not bind DNA autonomously. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Serum response factor (SRF) is a transcription factor that binds the serum response element (SRE), a sequence that mediates the transient response of many cellular genes to growth stimulation. SRF-binding sites are also constitutive promoter elements in many muscle-specific promoters. At the c-Fos SRE, formation of a ternary complex containing SRF and its accessory protein p62TCF appears to be important for signal transduction. Two related Ets domain proteins, Elk-1 and SRF accessory protein-1 (SAP-1), have DNA binding properties identical to that of p62TCF. Elk-1 and SAP-1 contain two homologous regions of which the two amino terminal regions, the Ets domain (box A) and the B box, mediate ternary complex formation with SRF. The third homologous region, the C box located toward the C-terminus of the proteins, contains conserved consensus phosphorylation sites for MAP kinases. |
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ELK4 Antibody Blocking Peptide(bs-13067P)-500ug
￥880
