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500ug
| 产品编号 | bs-17051P |
| 英文名称 | KIF24 Antibody Blocking Peptide |
| 中文名称 | 驱动蛋白家族成员24封闭多肽 |
| 英文别名 | bA571F15.4; C9orf48; Kif24; KIF24_HUMAN; kinesin family member 24; Kinesin-like protein KIF24; RP11-571F15.7. |
| 纯化方法 | HPLC |
| 亚基 | Interacts with CCP110 and CEP97. |
| 亚细胞定位 | Cytoplasm; cytoskeleton. |
| 相似性 | Belongs to the kinesin-like protein family. Contains 1 kinesin-motor domain. Contains 1 SAM (sterile alpha motif) domain. |
| 功能 | Microtubule-dependent motor protein that acts as a negative regulator of ciliogenesis by mediating recruitment of CCP110 to mother centriole in cycling cells, leading to restrict nucleation of cilia at centrioles. Mediates depolymerization of microtubules of centriolar origin, possibly to suppress aberrant cilia formation. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Kinesins, such as KIF24, are microtubule-dependent ATPases that function as molecular motors. They play important roles in intracellular vesicle transport and cell division (summary by Venturelli et al., 2010 [PubMed 20670673]).[supplied by OMIM, Feb 2011] |
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KIF24 Antibody Blocking Peptide(bs-17051P)-500ug
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